A vast international plot explodes when a beautiful Jane Doe is discovered naked in Times Square, completely covered in mysterious, intricate tattoos with no memory of who she is or how she got there. But there’s one tattoo that is impossible to miss: the name of FBI agent Kurt Weller, emblazoned across her back. “Jane,” Agent Weller and the rest of the FBI quickly realize that each mark on her body is a crime to solve, leading them closer to the truth about her identity and the mysteries to be revealed.
A beautiful, naked amnesiac is found in Times Square covered in mysterious tattoos, including one bearing the name of FBI Agent Kurt Weller. Special Agent Weller and his FBI team must decode the map of clues on Jane Doe's body in order to thwart a deadly terrorist attack. Who is Jane Doe - is she an asset or enemy? Who wiped her memory? And who is behind the tattoos?
The team unlocks a cryptic tattoo that points to Major Arthur Gibson, an Air Force pilot with a painful past and a lethal agenda. Jane continues to search for clues to her identity and is haunted when flashes of a disturbing memory force her to question her past. Meanwhile, Weller thinks he might know Jane's true identity.
An infamous crew of thieves almost pulls off the perfect jewel heist, except one thief - with a Navy SEAL tattoo identical to Jane's - is captured at the scene of the crime. Does this man know Jane? Meanwhile, Jane receives a visit - and an ambiguous warning - from the mysterious bearded man from her first memory as Weller and Mayfair struggle with Jane's role on the team.
Patterson and her puzzle-expert boyfriend, David, decode a tattoo clue that sends the team to the Centers for Disease Control (CDC). While at the CDC, the team discovers a hidden message on Jane's body that uncovers a plot that could have catastrophic global consequences. Meanwhile, Jane and Weller grow closer.
After a seemingly straightforward hostage situation turns out to have deeper international implications, the CIA and FBI find themselves racing against each other to apprehend the same criminal with a dark history. Carter expresses concern about Jane's trustworthiness, causing friction with Mayfair and testing Reade's loyalty to the team. Meeting Weller's family proves overwhelming for Jane as she grapples with her identity.
When an assassination leads the team to a dangerous app that allows criminals to track government vehicles, they have to work with the app's surprising creator to take it down. Jane and Weller attempt to keep their relationship professional. Zapata struggles with a moral issue.
One of Jane's tattoos sends the team to a remote location where they find themselves face to face with a dangerous criminal in a case that puts Jane and Weller's strained relationship to the test and threatens to expose Mayfair's secrets. Meanwhile, Patterson breaks the rules to solve a tattoo puzzle.
After a police officer is murdered, Patterson unlocks a disturbing tattoo that appears to have predicted his killing, and the team chases a violent clue trail to stop further attacks. Mayfair reveals secrets from her past to Weller, seriously testing their relationship.
Jane and Weller go undercover as a world-class assassin couple to prevent deadly information from getting into the wrong hands. The intimate assignment draws them closer than ever. Meanwhile, David embarks on a solo mission to win Patterson back, and Carter clashes with Mayfair over how to handle a dangerous individual.
In the thrilling mid-season finale the team goes after a group of sleeper spies that have just been activated and race to stop a slew of assassinations.
Jane reels from a series of massive revelations about her tattoos and grapples with whether to trust Oscar. Meanwhile, a tattoo leads the team to a shocking discovery in the Black Sea.
After a disturbed Iraq War vet shoots up a military base, the team exposes a sinister plot. As Jane and Weller race to stop a single-minded scientist, Jane recalls her own mysterious military past and contemplates a new relationship with Oscar.
After a tip reveals there's a mole within the FBI's New York Office, the team must hunt for the operative while facing extreme scrutiny from Inspector Fischer. The team's deepest secrets threaten to be exposed, and everyone is a potential suspect - but some, especially Jane Doe have more to hide.
An anonymous tip leads the team to investigate an urgent death row case, ultimately sending Zapata undercover. After nearly getting caught during the mole hunt, Jane considers leaving the FBI.
After a painting featuring one of Jane's tattoos is heisted from a gallery, the team discovers Jane is the real target. In order to protect her team, Jane goes AWOL.
After an armored truck is robbed, the team discovers that the stolen goods are chemical weapons and they must race to thwart a terrorist plot. Meanwhile, Jane grapples with a confusing memory of Weller - while growing even closer to Oscar. Meanwhile Patterson receives a phone call from someone from her past.
After Patterson discovers a hidden message in the New York Times crossword, she embarks on a tattoo scavenger hunt that leads her into danger. Oscar finally tells Jane more about who she was, and Weller seeks his Dad's opinion about who kidnapped Taylor Shaw.
In order to capture a dangerous international criminal, Jane and Weller are forced to collaborate with the only person he will meet: their former target, Rich DotCom. Jane must decide whether to risk hurting Weller by executing a morally questionable order from Oscar.
When a school shooting breaks out during the investigation of a tattoo, the team splits up to take down the shooter. Mayfair copes with some issues from her past.
When a mysterious young girl with a tattoo connection falls into Borden's care, he brings her case to the FBI team -- but her ties to a terrorist organization prove dangerous for all of them. Meanwhile, a conflicted Jane starts to grow close to Weller again, and friendship blossoms between Borden and Patterson.
The FBI is locked down when criminal hackers infiltrate the building, trapping the team inside SIOC. As they fight their way out, the close quarters force Mayfair, Zapata, Reade, and Sarah to confront personal conflicts.
After an abandoned baby is found with a tattoo identical to one of Jane's, the team races to piece together the child's identity and save dozens of infants. A furious Jane confronts Oscar about the outcome of his secret missions.
Weller searches for the truth within a heartbreaking and confounding assertion. Jane reaches out to a former suspect for help with Oscar. Meanwhile, the rest of the team struggles to help a friend...
After escaping from CIA custody, the team recaptures Jane and convinces her to become a triple-agent within her old terrorist organization where she unlocks some major secrets from her past, while recent betrayals from both sides threaten to tear her and the team apart for good.
The team races to stop a corrupt DEA agent from selling stinger missiles to a drug cartel as Weller fights to keep everyone together under the increasing pressures of Jane's rift with the others and the uncomfortable addition of Nas as co-leader.
Weller and the team must race the clock to stop a series of escalating New York City bombings, while Jane is forced to go on an assassination mission to prove her loyalty... or suffer the consequences.
Nas and Weller navigate their new dynamic as co-leaders during the team's hunt for a museum gala assassin, who turns out turns out to be harboring a dark secret. Jane starts to see a softer side of her old organization.
While Weller and Nas chase a fugitive whistleblower in Bulgaria, Jane goes on a Sandstorm mission with Roman. Reade and Zapata must deal with an urgent matter.
When Weller and Jane go missing during an undercover operation, the rest of the team must interrogate two criminals who hold the key to finding them. AUSA Weitz returns with a vendetta against the team.
Patterson is missing... and a newly amnesiac Roman is on the loose. Jane and Weller must race Shepherd – and the clock – to find them before it's too late.
A tattoo points the team toward a powerful collegiate secret society, but they can't infiltrate it without the help of one of its alumni...Rich Dotcom.
Jane and her new flame Oliver find themselves in a dangerous situation that exposes the secrets they've both been keeping. Uncertain if they can trust each other, the couple must stay alive while Weller and the team race to save them.
Zapata's transgressions catch up to her, sending her to jail alongside a potentially powerful Sandstorm asset named Devon. Weller and the team must go to exceptional lengths to help Zapata out.
While Jane and Weller hunt down a collective of dangerous computer hackers, Patterson and Rich Dot Com must work together to hide an explosive secret from their past.
Facing a threat within the FBI, the team is forced to run a covert operation out of Jane and Weller's apartment. A tattoo leads to a doctor with a deadly secret.
A surprising visit from Nas leads the team to investigate a dangerous piece of technology that was stolen from the NSA. Roman and Blake grow closer as they attend a high-stakes poker game.
When Patterson's investigation into a tattoo results in a horrible incident, she tries to figure out what went wrong - but quickly realizes all is not as it seems.
The team must decide whether to trust a prisoner who warns them of a dangerous plot. Zapata is caught between the FBI and the CIA. Roman and Crawford butt heads over how to handle a volatile situation.
A CIA source threatens to tear the team apart. Rich's place in the FBI is called into question. Roman and Crawford spend a day together under strange circumstances.
Jane and her team must fight for their lives when Roman sends deadly assassins after them. Meanwhile, Patterson goes on a date, Reade contends with the O.P.R. inquisitor, Jane and Weller go to dinner, and Zapata attends a funeral.
The team must partner with an oddball conspiracy theorist to keep Crawford from acquiring a deadly weapon; Roman struggles to maintain his personal life with Blake while completing a series of secret missions.
After receiving shocking news about Avery's father, Jane and Weller must hunt down an elusive criminal. Meanwhile, Patterson's father helps the team in the lab.
A decoded tattoo leads the team to a mysterious cache of dolls which turn out to be vehicles for biological weapons being sent around the world and now to the FBI. Jane exploits the fear of the weapons to advance her own plan to recover Shepherd.
The murder of a best-selling true crime novelist sends Jane and the team on a hunt for a serial killer detailed in the author's final manuscript, which also features lightly fictionalized versions of the FBI team.
Roman's clues lead to a billionaire hypochondriac with stem cells that could cure Jane, who is now on her deathbed. Patterson and Rich offer to trade the Book of Secrets for the stem cells -- but first they'll have to get it.
Jane and Weller's romantic getaway is cut short when the team must stop Madeline Burke's plans to blow up a building and crash a plane that turns out to be more than the average commercial airliner.
Patterson's father, Bill Nye, returns for a case that pits the team against a pestiferous foe. Zapata goes rogue with an old friend. Jane and Weller continue their search for the hooded figure.
The team discovers an international conspiracy when a deadly weapon is stolen, Jane supports Weller when someone from his past dredges up painful memories, and Patterson and Rich contend with their newly released hacker accomplice.
A horrifying and vengeful villain threatens the FBI. Weller considers his priorities. Zapata and Reade try to navigate their living situation. Patterson explores a budding interest.
The team sets out on an international mission to stop an attack from spreading. Madeline attempts to turn the tables as internal conflict threatens relationships within the team.
Jane tries to pick up the pieces after the explosive finale in Iceland. She gets a strange message from an unknown ally that allows her to mount a rescue mission to free Rich Dotcom from a CIA black-site... but she'll need the help from her old rival Sho Akhtar.
Jane and the team reach out to Patterson's father in the hope of gaining access to a high-level conference in Finland where they hope to bring Matthew Weitz to their side.
When an op goes bad, the team must deal with a proverbial monster in their house before it can take them down one by one. Meanwhile, Director Weitz is forced into a tense game of psychological chess as Madeline Burke attempts to assess his loyalty and root out a potential mole at the FBI.
In order to stop a terrorist group from procuring a deadly chemical weapon, the team must remember key details from their first days at the FBI. Meanwhile, Weller worries after he gets scary news about the health of his daughter.
When Jane is shot and Weller is kidnapped, the team must fight to save both of their lives while maintaining the secrecy of their hidden base. Meanwhile, Weller is haunted by some dark ghosts from the past.
When Ice Cream, the Icelandic fixer, returns to collect his debt, the team is forced into a life and death race around the world to solve a series of puzzles and recover the infamous stolen Gardner paintings.
In an effort to stop Madeline from shipping two planes full of ZIP to the US, the team splits up into a high-stakes undercover mission where they intercept Madeline's son. Meanwhile, Madeline interrogates an old ally to get information on Kurt and the team.
The team scrambles to get ahead of Madeline and Ivy as they close in on the bunker's location, but someone on the inside is feeding Madeline information. As her plan takes shape, the team may be forced to take desperate measures.
With the surviving members of the team captured and held in FBI custody, Madeline and Ivy are in the final stages of their plan, but a few unlikely allies come out from the woodwork, trying to stop her before it's too late.
As Ivy races to retrieve the devastating stash of ZIP bombs, the remaining members of the team must rely on the help of a longtime thorn in their side, the very unstable genius Kathy Gustafson.
43 min 
